If you have never experienced depression, it is hard to understand how someone with friends, prospects and ambitions can find themselves with a crushing weight on their chest, unable to enjoy anything in life, and even considering ending it all.

Kelly Osbourne will speak to sufferers and gain their perspective on their depression and the reasons behind it. Hearing from those who have sought help or helped themselves, we'll find out how they learnt to see the light again.

MUSIC & FACTUAL

Broadcast on Radio 1 in February 2008